HSP70 1A anticorps (C-Term)

N° du produit ABIN3020878

Détail du produit anti-HSP70 1A anticorps

Antigène: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSP70 1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: NALESYAFNM KSAVEDEGLK GKISEADKKK VLDKCQEVIS WLDANTLAEK DEFEHKRKEL EQVCNPIISG LYQGAGGPGP GGFGAQGPKG GSGSGPTIEE VD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 540 to the C-terminus of human HSP70/HSPA1 (NP_005336.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-HSP70 1A (ABIN3020878)

Ding, Chen, Zhang, Huang, Zang, Li, Li, Wong: "Regulation of Ubiquitin-like with Plant Homeodomain and RING Finger Domain 1 (UHRF1) Protein Stability by Heat Shock Protein 90 Chaperone Machinery." dans: The Journal of biological chemistry, Vol. 291, Issue 38, pp. 20125-35, (2017) (PubMed).

Geng, Li, Huang, Chai, Zheng, Li, Jiang: "Functional analysis of HSPA1A and HSPA8 in parturition." dans: Biochemical and biophysical research communications, Vol. 483, Issue 1, pp. 371-379, (2017) (PubMed).

Wang, Yu, Wang, Li, Li, Wang, Song, Chu, Li: "Gold-nanorods-siRNA nanoplex for improved photothermal therapy by gene silencing." dans: Biomaterials, Vol. 78, pp. 27-39, (2016) (PubMed).

Zhou, Jiang, Dong, Yan, You, Su, Gong: "The proteins interacting with C-terminal of μ receptor are identified by bacterial two-hybrid system from brain cDNA library in morphine-dependent rats." dans: Life sciences, Vol. 143, pp. 156-67, (2016) (PubMed).

Ye, Chen, Zhang, Miao, Zohaib, Xu, Chen, Cao: "Heat shock protein 70 is associated with replicase complex of Japanese encephalitis virus and positively regulates viral genome replication." dans: PLoS ONE, Vol. 8, Issue 9, pp. e75188, (2013) (PubMed).

Détails sur HSP70 1A

Antigène: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Autre désignation: HSPA1A (HSPA1A Produits)

Sujet: This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.,HSPA1A,HEL-S-103,HSP70-1,HSP70-1A,HSP70.1,HSP70I,HSP72,HSPA1,HSP70,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,HSPA1A

Poids moléculaire: 70 kDa

ID gène: 3303

UniProt: P0DMV8

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process