Insulin Receptor anticorps (AA 1130-1230)
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- Antigène Voir toutes Insulin Receptor (INSR) Anticorps
- Insulin Receptor (INSR)
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Épitope
- AA 1130-1230
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Insulin Receptor est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- PPTLQEMIQM AAEIADGMAY LNAKKFVHRD LAARNCMVAH DFTVKIGDFG MTRDIYETDY YRKGGKGLLP VRWMAPESLK DGVFTTSSDM WSFGVVLWEI T
- Réactivité croisée
- Humain, Souris
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- A synthetic peptide corresponding to a sequence within amino acids 1130-1230 of human Insulin Receptor (NP_000199.2).
- Isotype
- IgG
- Top Product
- Discover our top product INSR Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid freeze / thaw cycles
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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Abnormal gene methylation during embryonic development after preimplantation genetic testing increases risk of liver-derived insulin resistance." dans: Annals of the New York Academy of Sciences, (2018) (PubMed).
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Abnormal gene methylation during embryonic development after preimplantation genetic testing increases risk of liver-derived insulin resistance." dans: Annals of the New York Academy of Sciences, (2018) (PubMed).
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- Antigène
- Insulin Receptor (INSR)
- Autre désignation
- INSR (INSR Produits)
- Sujet
- This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.,CD220,HHF5,INSR,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Insulin and insulin-like,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Immunology & Inflammation,CD markers,Neuroscience,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,INSR
- Poids moléculaire
- 155 kDa/156 kDa
- ID gène
- 3643
- UniProt
- P06213
- Pathways
- Signalisation NF-kappaB, Signalisation RTK, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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