Clathrin Heavy Chain (CLTC) anticorps

N° du produit ABIN302098

Détail du produit

Antigène: Clathrin Heavy Chain (CLTC)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Specificité: The antibody BF-06 recognizes clathrin heavy chain, an ubiquitously expressed 180 kDa intracellular protein involved in receptor-mediated endocytosis.

Réactivité croisée (Details): Human, Porcine, Mouse, Rat, Bovine, Other not determined

Purification: Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Pureté: > 95 % (by SDS-PAGE)

Clone: BF-06

Isotype: IgM

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 2-5 μg/mL, positive control: human blood leukocytes. Intracellular staining.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Référence

Mac?rek, Zíková, Dráberová, Dráber: "Monoclonal antibody BF-06 against the heavy chain of clathrin." dans: Folia biologica, Vol. 49, Issue 6, pp. 238-40, (2004) (PubMed).

Détail du antigène

Antigène: Clathrin Heavy Chain (CLTC)

Autre désignation: Clathrin heavy chain (CLTC Produits)

Synonymes: anticorps CHC, anticorps Chc, anticorps CHC17, anticorps CLH-17, anticorps CLTCL2, anticorps Hc, anticorps CLTC, anticorps 3110065L21Rik, anticorps R74732, anticorps F11B9.30, anticorps cb1033, anticorps cltc, anticorps wu:fc03e11, anticorps wu:fc49a11, anticorps wu:fd07f02, anticorps clathrin heavy chain, anticorps Probable clathrin heavy chain 1, anticorps putative clathrin heavy chain, anticorps clathrin heavy chain 1, anticorps clathrin heavy chain Chc1, anticorps clathrin, heavy polypeptide (Hc), anticorps Clathrin, heavy chain, anticorps clathrin, heavy chain a (Hc), anticorps clathrin, heavy chain (Hc) L homeolog, anticorps CHC1, anticorps chc-1, anticorps CLTC, anticorps Chc, anticorps TP03_0480, anticorps LOC5578293, anticorps LMJF_36_1630, anticorps CpipJ_CPIJ014882, anticorps CNJ03270, anticorps ATEG_05434, anticorps CMU_025200, anticorps PMAA_094250, anticorps SJAG_02282, anticorps Smp_154420.1, anticorps PAAG_00730, anticorps MCYG_06136, anticorps VDBG_05048, anticorps MGYG_04658, anticorps cgd8_1270, anticorps Tc00.1047053506167.50, anticorps CHC, anticorps Cltc, anticorps AT3G11130, anticorps cltca, anticorps cltc.L

Sujet: Clathrin heavy chain,Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis.,CHC, CLHC, MRD56

ID gène: 1213

UniProt: Q00610