ITGA4 anticorps (C-Term)

N° du produit ABIN3021106

Détail du produit anti-ITGA4 anticorps

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: FLCNFGKMES GKEASVHIQL EGRPSILEMD ETSALKFEIR ATGFPEPNPR VIELNKDENV AHVLLEGLHH QRPKRYFTIV IISSSLLLGL IVLLLISYVM WKAGFFKRQY KSILQEENRR DSWSYINSKS NDD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 900 to the C-terminus of human Integrin alpha 4 (ITGA4/CD49d) (NP_000876.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ITGA4

Antigène: ITGA4 (Integrin alpha 4 (ITGA4))

Autre désignation: ITGA4 (ITGA4 Produits)

Synonymes: anticorps CD49D, anticorps IA4, anticorps LOC100219853, anticorps integrin subunit alpha 4, anticorps integrin alpha 4, anticorps integrin subunit alpha 4 S homeolog, anticorps ITGA4, anticorps Itga4, anticorps itga4.S

Sujet: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.,ITGA4,CD49D,IA4,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Neural Stem Cells,ITGA4

Poids moléculaire: 21 kDa/114 kDa

ID gène: 3676

UniProt: P13612

Pathways: Integrin Complex