anticorps KREV-1, anticorps KREV1, anticorps RAP1, anticorps SMGP21, anticorps AI848598, anticorps G-22K, anticorps Krev-1, anticorps Rap1, anticorps RAP-1A, anticorps rap 1A, anticorps wu:fc66g06, anticorps zgc:86676, anticorps krev-1, anticorps krev1, anticorps rap1, anticorps RAP1A, member of RAS oncogene family, anticorps RAS-related protein 1a, anticorps RAP1A, member of RAS oncogene family a, anticorps RAP1A, member of RAS oncogene family L homeolog, anticorps RAP1A, anticorps Rap1a, anticorps rap1aa, anticorps rap1a.L
Sujet
This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.,RAP1A,C21KG,G-22K,KREV-1,KREV1,RAP1,SMGP21,Signal Transduction,G protein signaling,Signal Transduction,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,RAP1A