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PPP3CA anticorps (AA 1-511)
PPP3CA
Reactivité: Humain
WB, IF
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN3021336
Détail du produit anti-PPP3CA anticorps
(cache)
Antigène
Voir toutes PPP3CA Anticorps
PPP3CA
(Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))
Épitope
Tous les épitopes à travers PPP3CA Anticorps.
AA 1-511
Reactivité
Toutes les réactivités sur PPP3CA Anticorps
Humain
Hôte
Toutes les hôtes sur PPP3CA Anticorps
Lapin
Clonalité
Toutes les clonalités sur PPP3CA Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers PPP3CA Anticorps
Cet anticorp PPP3CA est non-conjugé
Application
Tous les applications à travers PPP3CA Anticorps.
Western Blotting (WB), Immunofluorescence (IF)
Séquence
MSEPKAIDPK LSTTDRVVKA VPFPPSHRLT AKEVFDNDGK PRVDILKAHL MKEGRLEESV ALRIITEGAS ILRQEKNLLD IDAPVTVCGD IHGQFFDLMK LFEVGGSPAN TRYLFLGDYV DRGYFSIECV LYLWALKILY PKTLFLLRGN HECRHLTEYF TFKQECKIKY SERVYDACMD AFDCLPLAAL MNQQFLCVHG GLSPEINTLD DIRKLDRFKE PPAYGPMCDI LWSDPLEDFG NEKTQEHFTH NTVRGCSYFY SYPAVCEFLQ HNNLLSILRA HEAQDAGYRM YRKSQTTGFP SLITIFSAPN YLDVYNNKAA VLKYENNVMN IRQFNCSPHP YWLPNFMDVF TWSLPFVGEK VTEMLVNVLN ICSDDELGSE EDGFDGATAA ARKEVIRNKI RAIGKMARVF SVLREESESV LTLKGLTPTG MLPSGVLSGG KQTLQSAIKG FSPQHKITSF EEAKGLDRIN ERMPPRRDAM PSDANLNSIN KALTSETNGT DSNGSNSSNI Q
Réactivité croisée
Humain, Souris
Attributs du produit
Polyclonal Antibodies
Immunogène
Recombinant fusion protein containing a sequence corresponding to amino acids 1-511 of human Calcineurin A (NP_001124163.1).
Isotype
IgG
Top Product
Discover our top product PPP3CA Anticorps primaire
Alternatives
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anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (Middle Region) antibody
PPP3CA
Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cheval, Poisson zèbre (Danio rerio), Cobaye
WB
Hôte: Lapin
Polyclonal
unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (N-Term) antibody
PPP3CA
Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cheval, Porc, Poisson zèbre (Danio rerio)
WB
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
(cache)
Indications d'application
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid freeze / thaw cycles
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Références pour anticorps anti-PPP3CA (ABIN3021336)
(cache)
Chen, Wang, Long, Jia, Zhang, Deng, Li, Han, Wang : "Fasting-induced hormonal regulation of lysosomal function. " dans: Cell research , Vol. 27 , Issue 6 , pp. 748-763 , (2018 ) (PubMed ).
Détails sur PPP3CA
(cache)
Antigène
PPP3CA
(Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))
Autre désignation
PPP3CA (PPP3CA Produits )
Synonymes
anticorps CALN, anticorps CALNA, anticorps CALNA1, anticorps CCN1, anticorps CNA1, anticorps PPP2B, anticorps 2900074D19Rik, anticorps AI841391, anticorps AW413465, anticorps CN, anticorps Caln, anticorps Calna, anticorps CnA, anticorps Calna1, anticorps calcineurin, anticorps caln, anticorps calna, anticorps calna1, anticorps ccn1, anticorps cna1, anticorps ppp2b, anticorps fj46e08, anticorps si:dkeyp-79c2.2, anticorps wu:fj46e08, anticorps ppp3ca, anticorps protein phosphatase 3 catalytic subunit alpha, anticorps protein phosphatase 3, catalytic subunit, alpha isoform, anticorps protein phosphatase 3, catalytic subunit, alpha isozyme, anticorps protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha), anticorps protein phosphatase 3, catalytic subunit, alpha isozyme L homeolog, anticorps serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, anticorps PPP3CA, anticorps Ppp3ca, anticorps ppp3ca, anticorps ppp3ca.L, anticorps LOC100205420
Sujet
Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+-mediated signals. Many of the substrates contain a PxIxIT motif and/or a LxVP motif. In response to increased Ca(2+ levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation. In response to increased Ca(2+ levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion. Dephosphorylates heat shock protein HSPB1 (By similarity. Dephosphorylates and activates transcription factor NFATC1. In response to increased Ca(2+ levels, regulates NFAT-mediated transcription probably by dephosphorylating NFAT and promoting its nuclear translocation. Dephosphorylates and inactivates transcription factor ELK1. Dephosphorylates DARPP32. May dephosphorylate CRTC2 at 'Ser-171' resulting in CRTC2 dissociation from 14-3-3 proteins. Dephosphorylates transcription factor TFEB at 'Ser-211' following Coxsackievirus B3 infection, promoting nuclear translocation.,PPP3CA,CALN,CALNA,CALNA1,CCN1,CNA1,PPP2B,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,Neurodegenerative Diseases,PPP3CA
Poids moléculaire
31 kDa/51 kDa/52 kDa/57 kDa/58 kDa
ID gène
5530
UniProt
Q08209
Pathways
Signalisation RTK , Signalisation WNT , Fc-epsilon Receptor Signaling Pathway , Negative Regulation of Hormone Secretion , Carbohydrate Homeostasis , Synaptic Membrane , Skeletal Muscle Fiber Development , Protein targeting to Nucleus , VEGF Signaling , BCR Signaling
Vus récemment
(cache)