TTR anticorps (AA 21-147)

N° du produit ABIN3021474

Détail du produit anti-TTR anticorps

Antigène: TTR (Transthyretin (TTR))

Épitope: AA 21-147

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: GPTGTGESKC PLMVKVLDAV RGSPAINVAV HVFRKAADDT WEPFASGKTS ESGELHGLTT EEEFVEGIYK VEIDTKSYWK ALGISPFHEH AEVVFTANDS GPRRYTIAAL LSPYSYSTTA VVTNPKE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 21-147 of human TTR (NP_000362.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-TTR (ABIN3021474)

Tesch, Abdirama, Grießbach, Brand, Goerlich, Humrich, Bacher, Hiepe, Riemekasten, Enghard: "Identification and characterization of antigen-specific CD4+ T cells targeting renally expressed antigens in human lupus nephritis with two independent methods." dans: Scientific reports, Vol. 10, Issue 1, pp. 21312, (2020) (PubMed).

Détails sur TTR

Antigène: TTR (Transthyretin (TTR))

Autre désignation: TTR (TTR Produits)

Synonymes: anticorps zgc:103583, anticorps TTR, anticorps LOC100226992, anticorps CTS, anticorps CTS1, anticorps HsT2651, anticorps PALB, anticorps TBPA, anticorps AA408768, anticorps AI787086, anticorps D17860, anticorps prealbumin, anticorps Lr1, anticorps Tbpa, anticorps Prealbumin, anticorps xTTR, anticorps transthyretin (prealbumin, amyloidosis type I), anticorps transthyretin, anticorps Transthyretin, anticorps transthyretin (prealbumin, amyloidosis type 1), anticorps transthyretin-like, anticorps transthyretin L homeolog, anticorps ttr, anticorps TTR, anticorps vpb38, anticorps MRAD2831_RS38185, anticorps Caci_4246, anticorps LOC100226992, anticorps Ttr, anticorps ttr.L

Sujet: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.,TTR,CTS,CTS1,HEL111,HsT2651,PALB,TBPA,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Blood,Serum Proteins,TTR

Poids moléculaire: 15 kDa

ID gène: 7276

UniProt: P02766

Pathways: Hormone Transport