WT1 anticorps (AA 1-302)

N° du produit ABIN3021698

Détail du produit anti-WT1 anticorps

Antigène: WT1 (Wilms Tumor 1 (WT1))

Épitope: AA 1-302

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MEKGYSTVTF DGTPSYGHTP SHHAAQFPNH SFKHEDPMGQ QGSLGEQQYS VPPPVYGCHT PTDSCTGSQA LLLRTPYSSD NLYQMTSQLE CMTWNQMNLG ATLKGVAAGS SSSVKWTEGQ SNHSTGYESD NHTTPILCGA QYRIHTHGVF RGIQDVRRVP GVAPTLVRSA SETSEKRPFM CAYPGCNKRY FKLSHLQMHS RKHTGEKPYQ CDFKDCERRF SRSDQLKRHQ RRHTGVKPFQ CKTCQRKFSR SDHLKTHTRT HTGEKPFSCR WPSCQKKFAR SDELVRHHNM HQRNMTKLQL AL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-302 of human WT1 (NP_001185480.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-WT1 (ABIN3021698)

Wang, Luo, Du, Shu, Guo, Li: "Nuclear paraspeckle assembly transcript 1 promotes the podocyte injury via targeting miR-23b-3p/B-cell lymphoma-2 interacting protein 3 like axis." dans: Renal failure, Vol. 44, Issue 1, pp. 1961-1975, (2022) (PubMed).

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: WT1 (WT1 Produits)

Synonymes: anticorps AWT1, anticorps EWS-WT1, anticorps GUD, anticorps NPHS4, anticorps WAGR, anticorps WIT-2, anticorps WT33, anticorps CWT1, anticorps WT1, anticorps XWT1a, anticorps wt-1, anticorps wt1, anticorps xWT1, anticorps WT-1, anticorps gud, anticorps wagr, anticorps wt33, anticorps xwt1, anticorps wit-2, anticorps si:ch211-160j6.3, anticorps zgc:152697, anticorps D630046I19Rik, anticorps Wt-1, anticorps XWT1b, anticorps XeWT1, anticorps Wilms tumor 1, anticorps Wilms tumor 1 S homeolog, anticorps wilms tumor 1b, anticorps Wilms tumor protein, anticorps Wilms tumor 1 homolog, anticorps Wilms tumor 1 L homeolog, anticorps WT1, anticorps wt1.S, anticorps wt1, anticorps wt1b, anticorps Wt1, anticorps wt1.L

Sujet: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.,WT1,AWT1,EWS-WT1,GUD,NPHS4,WAGR,WIT-2,WT33,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor biomarkers,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,WT1

Poids moléculaire: 33 kDa/34 kDa/47 kDa/48 kDa/49 kDa/55 kDa/56 kDa

ID gène: 7490

UniProt: P19544

Pathways: Tube Formation