F11R anticorps (AA 30-238)

N° du produit ABIN3021823

Détail du produit anti-F11R anticorps

Antigène: F11R (F11 Receptor (F11R))

Épitope: AA 30-238

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp F11R est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: TVHSSEPEVR IPENNPVKLS CAYSGFSSPR VEWKFDQGDT TRLVCYNNKI TASYEDRVTF LPTGITFKSV TREDTGTYTC MVSEEGGNSY GEVKVKLIVL VPPSKPTVNI PSSATIGNRA VLTCSEQDGS PPSEYTWFKD GIVMPTNPKS TRAFSNSSYV LNPTTGELVF DPLSASDTGE YSCEARNGYG TPMTSNAVRM EAVERNVGV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 30-238 of human F11R (NP_058642.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-F11R (ABIN3021823)

Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." dans: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).

Détails sur F11R

Antigène: F11R (F11 Receptor (F11R))

Autre désignation: F11R (F11R Produits)

Synonymes: anticorps CD321, anticorps JAM, anticorps JAM1, anticorps JAMA, anticorps JCAM, anticorps KAT, anticorps PAM-1, anticorps 9130004G24, anticorps AA638916, anticorps ESTM33, anticorps JAM-1, anticorps JAM-A, anticorps Jcam, anticorps Jcam1, anticorps Ly106, anticorps Jam1, anticorps F11 receptor, anticorps F11R, anticorps F11r

Sujet: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.,F11R,CD321,JAM,JAM1,JAMA,JCAM,KAT,PAM-1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,Immunology & Inflammation,CD markers,Cardiovascular,Blood,F11R

Poids moléculaire: 27 kDa/32 kDa

ID gène: 50848

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization