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RENT1/UPF1 anticorps (AA 270-370)

UPF1 Reactivité: Humain WB, IF, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3022069
  • Antigène Voir toutes RENT1/UPF1 (UPF1) Anticorps
    RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
    Épitope
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 270-370
    Reactivité
    • 53
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 47
    • 3
    • 3
    Lapin
    Clonalité
    • 46
    • 7
    Polyclonal
    Conjugué
    • 29
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RENT1/UPF1 est non-conjugé
    Application
    • 25
    • 16
    • 14
    • 14
    • 8
    • 8
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Séquence
    KENPSATLED LEKPGVDEEP QHVLLRYEDA YQYQNIFGPL VKLEADYDKK LKESQTQDNI TVRWDLGLNK KRIAYFTLPK TDSDMRLMQG DEICLRYKGD L
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 270-370 of human UPF1/RENT1 (NP_002902.2).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
    Autre désignation
    UPF1 (UPF1 Produits)
    Sujet
    This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.,UPF1,HUPF1,NORF1,RENT1,pNORF1,smg-2,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,UPF1
    Poids moléculaire
    123 kDa/124 kDa
    ID gène
    5976
    UniProt
    Q92900
    Pathways
    SARS-CoV-2 Protein Interactome
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