Glucose-6-Phosphate Dehydrogenase anticorps (AA 246-545)

N° du produit ABIN3022095

Détail du produit anti-Glucose-6-Phosphate Dehydrogenase anticorps

Antigène: Glucose-6-Phosphate Dehydrogenase (G6PD)

Épitope: AA 246-545

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glucose-6-Phosphate Dehydrogenase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: FANRIFGPIW NRDNIACVIL TFKEPFGTEG RGGYFDEFGI IRDVMQNHLL QMLCLVAMEK PASTNSDDVR DEKVKVLKCI SEVQANNVVL GQYVGNPDGE GEATKGYLDD PTVPRGSTTA TFAAVVLYVE NERWDGVPFI LRCGKALNER KAEVRLQFHD VAGDIFHQQC KRNELVIRVQ PNEAVYTKMM TKKPGMFFNP EESELDLTYG NRYKNVKLPD AYERLILDVF CGSQMHFVRS DELREAWRIF TPLLHQIELE KPKPIPYIYG SRGPTEADEL MKRVGFQYEG TYKWVNPHKL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 246-545 of human G6PD (NP_000393.4).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Glucose-6-Phosphate Dehydrogenase (ABIN3022095)

Yang, He, Yao, Tan, Zhu, Li, Guo, Wei: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." dans: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).

Wang, Liang, Lian, Liu, Zhao, Xuan, Guo, Liu, Yang, Dong, Liu, Liu, Zhang: "Identification of proteins responsible for adriamycin resistance in breast cancer cells using proteomics analysis." dans: Scientific reports, Vol. 5, pp. 9301, (2016) (PubMed).

Détails sur Glucose-6-Phosphate Dehydrogenase

Antigène: Glucose-6-Phosphate Dehydrogenase (G6PD)

Autre désignation: G6PD (G6PD Produits)

Synonymes: anticorps G6PD1, anticorps g6pd, anticorps G6pd, anticorps G6pdx, anticorps g6pdh, anticorps g6pd2, anticorps fj78b06, anticorps wu:fj78b06, anticorps si:dkey-90a13.8, anticorps BA3433, anticorps CORTRD1, anticorps G6PDH, anticorps GDH, anticorps G28A, anticorps G6PD, anticorps Gpdx, anticorps glucose-6-phosphate dehydrogenase, anticorps glucose-6-phosphate 1-dehydrogenase, anticorps glucose-6-phosphate 1-dehydrogenase (G6PD), anticorps glucose-6-P dehydrogenase, anticorps glucose-6-phosphate dehydrogenase L homeolog, anticorps glucose-6-phosphate 1-dehydrogenase Zwf, anticorps hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase, anticorps glucose-6-phosphate dehydrogenase X-linked, anticorps G6PD, anticorps g6pd, anticorps g6pD, anticorps zwf, anticorps LOC100120232, anticorps LACBIDRAFT_188936, anticorps G6pd, anticorps g6pd.L, anticorps CNG03280, anticorps Tb10.70.5200, anticorps H6PD, anticorps G6pdx, anticorps H6pd

Sujet: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.,G6PD,G6PD1,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Heart,Cardiac metabolism,Cardiovascular diseases,Heart disease,G6PD

Poids moléculaire: 59 kDa/62 kDa/63 kDa

ID gène: 2539

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones