Renin anticorps (AA 24-160)

N° du produit ABIN3022188

Détail du produit anti-Renin anticorps

Antigène: Renin (REN)

Épitope: AA 24-160

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Renin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LPTDTTTFKR IFLKRMPSIR ESLKERGVDM ARLGPEWSQP MKRLTLGNTT SSVILTNYMD TQYYGEIGIG TPPQTFKVVF DTGSSNVWVP SSKCSRLYTA CVYHKLFDAS DSSSYKHNGT ELTLRYSTGT VSGFLSQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 24-160 of human Renin (NP_000528.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Renin

Antigène: Renin (REN)

Autre désignation: REN (REN Produits)

Synonymes: anticorps HNFJ2, anticorps RATRENAA, anticorps RENAA, anticorps Ren1, anticorps D19352, anticorps Ren, anticorps Ren-1, anticorps Ren-A, anticorps Ren1c, anticorps Ren1d, anticorps Rn-1, anticorps Rnr, anticorps renin, anticorps renin 1 structural, anticorps REN, anticorps Ren, anticorps Ren1, anticorps ren

Sujet: Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.,REN,HNFJ2,renin,Renin,Cardiovascular,Blood,Blood Pressure regulation,REN

Poids moléculaire: 44 kDa/45 kDa

ID gène: 5972

UniProt: P00797

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour