alpha Adducin anticorps (AA 60-300)

N° du produit ABIN3022200

Détail du produit anti-alpha Adducin anticorps

Antigène: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Épitope: AA 60-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Adducin est non-conjugé

Application: Western Blotting (WB)

Séquence: MILQSPAFCE ELESMIQEQF KKGKNPTGLL ALQQIADFMT TNVPNVYPAA PQGGMAALNM SLGMVTPVND LRGSDSIAYD KGEKLLRCKL AAFYRLADLF GWSQLIYNHI TTRVNSEQEH FLIVPFGLLY SEVTASSLVK INLQGDIVDR GSTNLGVNQA GFTLHSAIYA ARPDVKCVVH IHTPAGAAVS AMKCGLLPIS PEALSLGEVA YHDYHGILVD EEEKVLIQKN LGPKSKVLIL R

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 60-300 of human ADD1 (NP_054908.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur alpha Adducin

Antigène: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Autre désignation: ADD1 (ADD1 Produits)

Synonymes: anticorps ADDA, anticorps AI256389, anticorps alpha-adducin, anticorps bZ1H20.1, anticorps cb787, anticorps zgc:158352, anticorps add2, anticorps adda, anticorps add1-a, anticorps ADD1, anticorps adducin 1, anticorps adducin 1 (alpha), anticorps adducin 1 S homeolog, anticorps ADD1, anticorps Add1, anticorps add1, anticorps add1.S

Sujet: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.,ADD1,ADDA,adducin 1,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cytoskeleton,Neuroscience,Calcium Signaling,ADD1

Poids moléculaire: 56 kDa/69 kDa/73 kDa/80 kDa/84 kDa

ID gène: 118

UniProt: P35611

Pathways: Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling