SELPLG anticorps (AA 40-280)

N° du produit ABIN3022340

Détail du produit anti-SELPLG anticorps

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Épitope: AA 40-280

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SELPLG est non-conjugé

Application: Western Blotting (WB)

Séquence: RRQATEYEYL DYDFLPETEP PEMLRNSTDT TPLTGPGTPE STTVEPAARR STGLDAGGAV TELTTELANM GNLSTDSAAM EIQTTQPAAT EAQTTPLAAT EAQTTRLTAT EAQTTPLAAT EAQTTPPAAT EAQTTQPTGL EAQTTAPAAM EAQTTAPAAM EAQTTPPAAM EAQTTQTTAM EAQTTAPEAT EAQTTQPTAT EAQTTPLAAM EALSTEPSAT EALSMEPTTK RGLFIPFSVS S

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 40-280 of human SELPLG (NP_002997.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: SELPLG (SELPLG Produits)

Synonymes: anticorps CD162, anticorps CLA, anticorps PSGL-1, anticorps PSGL1, anticorps SELPLG, anticorps SELPG, anticorps Psgl-1, anticorps Psgl1, anticorps Selp1, anticorps Selpl, anticorps selectin P ligand, anticorps selectin, platelet (p-selectin) ligand, anticorps clasper, anticorps SELPLG, anticorps Selplg, anticorps cla

Sujet: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.,SELPLG,CD162,CLA,PSGL-1,PSGL1,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Immunology & Inflammation,CD markers,Cardiovascular,SELPLG

Poids moléculaire: 43 kDa/44 kDa

ID gène: 6404

UniProt: Q14242