KPNA1 anticorps (AA 1-300)

N° du produit ABIN3022472

Détail du produit anti-KPNA1 anticorps

Antigène: KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))

Épitope: AA 1-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MTTPGKENFR LKSYKNKSLN PDEMRRRREE EGLQLRKQKR EEQLFKRRNV ATAEEETEEE VMSDGGFHEA QISNMEMAPG GVITSDMIEM IFSKSPEQQL SATQKFRKLL SKEPNPPIDE VISTPGVVAR FVEFLKRKEN CTLQFESAWV LTNIASGNSL QTRIVIQAGA VPIFIELLSS EFEDVQEQAV WALGNIAGDS TMCRDYVLDC NILPPLLQLF SKQNRLTMTR NAVWALSNLC RGKSPPPEFA KVSPCLNVLS WLLFVSDTDV LADACWALSY LSDGPNDKIQ AVIDAGVCRR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KPNA1 (NP_002255.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-KPNA1 (ABIN3022472)

Ye, Chen, Li, Zhao, He, Zohaib, Song, Deng, Zhang, Chen, Cao: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." dans: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).

Détails sur KPNA1

Antigène: KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))

Autre désignation: KPNA1 (KPNA1 Produits)

Synonymes: anticorps IPOA5, anticorps NPI-1, anticorps RCH2, anticorps SRP1, anticorps AW494490, anticorps NPI1, anticorps Rch2, anticorps mSRP1, anticorps si:ch211-161h7.7, anticorps karyopherin subunit alpha 1, anticorps importin alpha-1 subunit, anticorps karyopherin (importin) alpha 1, anticorps karyopherin alpha 1 (importin alpha 5), anticorps KPNA1, anticorps Kpna1, anticorps EHI_124900, anticorps kpna1

Sujet: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.,KPNA1,IPOA5,NPI-1,RCH2,SRP1,Signal Transduction,Immunology & Inflammation,KPNA1

Poids moléculaire: 60 kDa

ID gène: 3836

UniProt: P52294

Pathways: M Phase, Protein targeting to Nucleus