MCM6 anticorps (AA 562-821)

N° du produit ABIN3022687

Détail du produit anti-MCM6 anticorps

Antigène: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Épitope: AA 562-821

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM6 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Séquence: SIDRVYSLDD IRRYLLFARQ FKPKISKESE DFIVEQYKHL RQRDGSGVTK SSWRITVRQL ESMIRLSEAM ARMHCCDEVQ PKHVKEAFRL LNKSIIRVET PDVNLDQEEE IQMEVDEGAG GINGHADSPA PVNGINGYNE DINQESAPKA SLRLGFSEYC RISNLIVLHL RKVEEEEDES ALKRSELVNW YLKEIESEID SEEELINKKR IIEKVIHRLT HYDHVLIELT QAGLKGSTEG SESYEEDPYL VVNPNYLLED

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 562-821 of human MCM6 (NP_005906.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MCM6

Antigène: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Autre désignation: MCM6 (MCM6 Produits)

Synonymes: anticorps CG4039, anticorps DmMCM6, anticorps DmeMCM6, anticorps Dmel\\CG4039, anticorps MCM6, anticorps McM6, anticorps fs(1)K1214, anticorps mcm6, anticorps MCG40308, anticorps Mis5, anticorps P105MCM, anticorps Mcmd6, anticorps mis5, anticorps mmcm6, anticorps ASP-l1, anticorps D1Wsu22e, anticorps Minichromosome maintenance 6, anticorps DNA replication licensing factor MCM6, anticorps minichromosome maintenance complex component 6, anticorps minichromosome maintenance complex component 6 L homeolog, anticorps DNA replication licensing factor mcm-6, anticorps Mcm6, anticorps TP02_0113, anticorps PVX_114735, anticorps CMU_027970, anticorps MCM6, anticorps mcm6.L, anticorps mcm-6

Sujet: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood.,MCM6,MCG40308,Mis5,P105MCM,Epigenetics & Nuclear Signaling,MCM6

Poids moléculaire: 92 kDa

ID gène: 4175

UniProt: Q14566

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA