CTLA4 anticorps (AA 36-161)

N° du produit ABIN3022828

Détail du produit anti-CTLA4 anticorps

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Épitope: AA 36-161

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTLA4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: KAMHVAQPAV VLASSRGIAS FVCEYASPGK ATEVRVTVLR QADSQVTEVC AATYMMGNEL TFLDDSICTG TSSGNQVNLT IQGLRAMDTG LYICKVELMY PPPYYLGIGN GTQIYVIDPE PCPDSD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 36-161 of human CTLA4 (NP_005205.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CTLA4

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Autre désignation: CTLA4 (CTLA4 Produits)

Synonymes: anticorps CTLA-4, anticorps CTLA4, anticorps CD152, anticorps Cd152, anticorps Ctla-4, anticorps Ly-56, anticorps CD, anticorps CELIAC3, anticorps GRD4, anticorps GSE, anticorps IDDM12, anticorps sCTLA4, anticorps cytotoxic T-lymphocyte associated protein 4, anticorps cytotoxic T-lymphocyte-associated protein 4, anticorps CTLA4, anticorps Ctla4

Sujet: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.,CTLA4,ALPS5,CD,CD152,CELIAC3,CTLA-4,GRD4,GSE,IDDM12,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CTLA4

Poids moléculaire: 6 kDa/8 kDa/19 kDa/24 kDa

ID gène: 1493

UniProt: P16410

Pathways: Cancer Immune Checkpoints