HNF4A anticorps (AA 200-300)

N° du produit ABIN3022870

Détail du produit anti-HNF4A anticorps

Antigène: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Épitope: AA 200-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNF4A est non-conjugé

Application: Western Blotting (WB)

Séquence: EWAKYIPAFC ELPLDDQVAL LRAHAGEHLL LGATKRSMVF KDVLLLGNDY IVPRHCPELA EMSRVSIRIL DELVLPFQEL QIDDNEYAYL KAIIFFDPDA K

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human HNF4A (NP_000448.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-HNF4A (ABIN3022870)

Wei, Dai, Zhou, He, Yao, Zhao, Guo, Yang: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." dans: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).

Détails sur HNF4A

Antigène: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Autre désignation: HNF4A (HNF4A Produits)

Synonymes: anticorps HNF4A, anticorps HNF4alpha, anticorps CG9310, anticorps DmHNF4, anticorps Dmel\\CG9310, anticorps HNF-4, anticorps HNF-4(D), anticorps HNF4, anticorps Hnf-4, anticorps Hnf-4h, anticorps NR2A4, anticorps dHNF-4, anticorps dHNF4, anticorps Hnf4, anticorps Hnf4alpha, anticorps MODY1, anticorps Nr2a1, anticorps Tcf14, anticorps HNF4a7, anticorps HNF4a8, anticorps HNF4a9, anticorps MODY, anticorps NR2A1, anticorps NR2A21, anticorps TCF, anticorps TCF14, anticorps HNF-4alpha, anticorps fb58h09, anticorps id:ibd1279, anticorps wu:fb58h09, anticorps hnf4, anticorps nr2a1, anticorps hepatocyte nuclear factor 4 alpha, anticorps Hepatocyte nuclear factor 4, anticorps hepatic nuclear factor 4, alpha, anticorps hepatocyte nuclear factor 4, alpha, anticorps hepatocyte nuclear factor 4 alpha S homeolog, anticorps HNF4A, anticorps hnf4a, anticorps Hnf4, anticorps Hnf4a, anticorps hnf4a.S

Sujet: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.,HNF4A,FRTS4,HNF4,HNF4a7,HNF4a8,HNF4a9,HNF4alpha,MODY,MODY1,NR2A1,NR2A21,TCF,TCF14,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Wnt/β-Catenin Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cytochromes,AMPK Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Stem Cells,Cardiovascular,Blood,Coagulation,Lipids,HNF4A

Poids moléculaire: 43-56 kDa

ID gène: 3172

UniProt: P41235

Pathways: AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process