anticorps zgc:101624, anticorps 4921517J08Rik, anticorps 4930548B21Rik, anticorps GS4, anticorps MLZ-465, anticorps Spdy1, anticorps RINGO, anticorps SPDY1, anticorps RINGO3, anticorps RINGOA, anticorps SPY1, anticorps Gs4, anticorps Lm23, anticorps Spy1, anticorps speedy homolog A (Xenopus laevis), anticorps speedy/RINGO cell cycle regulator family member A, anticorps speedy/RINGO cell cycle regulator family, member A, anticorps SPDYA, anticorps spdya, anticorps Spdya
Sujet
Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. Mediates cell survival during the DNA damage process through activation of CDK2.,SPDYA,RINGO3,RINGOA,SPDY1,SPY1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,SPDYA