Histone 3 anticorps (C-Term)

N° du produit ABIN3023243

Détail du produit anti-Histone 3 anticorps

Antigène: Histone 3 (H3)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP)

Séquence: REIRRYQKST ELLIRKLPFQ RLMREIAQDF KTDLRFQSSA VMALQEACES YLVGLFEDTN LCVIHAKRVT IMPKDIQLAR RIRGERA

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human HIST3H3 (NP_003484.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200,ChIP,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Histone 3 (ABIN3023243)

Hou, Han, Fei, Gao, Qi, Cai, Qi: "Dietary Flavone Tectochrysin Exerts Anti-Inflammatory Action by Directly Inhibiting MEK1/2 in LPS-Primed Macrophages." dans: Molecular nutrition & food research, Vol. 62, Issue 2, (2018) (PubMed).

Tang, Guo, Zhu, Huang, Liu, Cai, Yu, Wang: "Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation." dans: International journal of oncology, Vol. 52, Issue 6, pp. 1899-1911, (2018) (PubMed).

Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." dans: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).

Su, Li, Lei, Wang, Zhao, Cai, Wang, Li, Wu: "The EZH1-SUZ12 complex positively regulates the transcription of NF-κB target genes through interaction with UXT." dans: Journal of cell science, Vol. 129, Issue 12, pp. 2343-53, (2017) (PubMed).

Yu, Tong, Luo, Xue, Mei, Ma, Yu, Mao, Kong, Yu, Li: "Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites." dans: PLoS ONE, Vol. 12, Issue 4, pp. e0175576, (2017) (PubMed).

Ji, Liu, Zhao, Liu, Guo, Guan, Zhou, Guo: "NF-κB Signaling is Involved in the Effects of Intranasally Engrafted Human Neural Stem Cells on Neurofunctional Improvements in Neonatal Rat Hypoxic-Ischemic Encephalopathy." dans: CNS neuroscience & therapeutics, Vol. 21, Issue 12, pp. 926-35, (2016) (PubMed).

Détails sur Histone 3

Antigène: Histone 3 (H3)

Autre désignation: Histone H3 (H3 Produits)

Synonymes: anticorps H-3, anticorps histocompatibility 3, anticorps H3

Sujet: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.,H3.4,H3/g,H3FT,H3t,HIST3H3,Histone H3,HIST1H3A,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Histone H3

Poids moléculaire: 15 kDa

ID gène: 8290

UniProt: Q16695