PLK1 anticorps (AA 304-603)

N° du produit ABIN3023352

Détail du produit anti-PLK1 anticorps

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Épitope: AA 304-603

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: FFTSGYIPAR LPITCLTIPP RFSIAPSSLD PSNRKPLTVL NKGLENPLPE RPREKEEPVV RETGEVVDCH LSDMLQQLHS VNASKPSERG LVRQEEAEDP ACIPIFWVSK WVDYSDKYGL GYQLCDNSVG VLFNDSTRLI LYNDGDSLQY IERDGTESYL TVSSHPNSLM KKITLLKYFR NYMSEHLLKA GANITPREGD ELARLPYLRT WFRTRSAIIL HLSNGSVQIN FFQDHTKLIL CPLMAAVTYI DEKRDFRTYR LSLLEEYGCC KELASRLRYA RTMVDKLLSS RSASNRLKAS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 304-603 of human PLK1 (NP_005021.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLK1

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Autre désignation: PLK1 (PLK1 Produits)

Synonymes: anticorps PLK, anticorps STPK13, anticorps plk, anticorps PLK-1, anticorps Plx1, anticorps stpk13, anticorps Plk, anticorps cb525, anticorps cb636, anticorps ik:tdsubc_2d1, anticorps wu:fb37g11, anticorps wu:fb76g03, anticorps xx:tdsubc_2d1, anticorps polo like kinase 1, anticorps polo like kinase 1 S homeolog, anticorps polo-like kinase 1, anticorps polo-like kinase 1 (Drosophila), anticorps Serine/threonine-protein kinase plk-1, anticorps PLK1, anticorps plk1.S, anticorps plk1, anticorps Plk1, anticorps plk-1

Sujet: The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis, hence, it is a target for cancer therapy.,PLK1,PLK,STPK13,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,G2/M DNA Damage Checkpoint,PLK1

Poids moléculaire: 68 kDa

ID gène: 5347

UniProt: P53350

Pathways: Cycle Cellulaire, M Phase