PDHA1 anticorps (AA 30-390)

N° du produit ABIN3023697

Détail du produit anti-PDHA1 anticorps

Antigène: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Épitope: AA 30-390

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDHA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Séquence: FANDATFEIK KCDLHRLEEG PPVTTVLTRE DGLKYYRMMQ TVRRMELKAD QLYKQKIIRG FCHLCDGQEA CCVGLEAGIN PTDHLITAYR AHGFTFTRGL SVREILAELT GRKGGCAKGK GGSMHMYAKN FYGGNGIVGA QVPLGAGIAL ACKYNGKDEV CLTLYGDGAA NQGQIFEAYN MAALWKLPCI FICENNRYGM GTSVERAAAS TDYYKRGDFI PGLRVDGMDI LCVREATRFA AAYCRSGKGP ILMELQTYRY HGHSMSDPGV SYRTREEIQE VRSKSDPIML LKDRMVNSNL ASVEELKEID VEVRKEIEDA AQFATADPEP PLEELGYHIY SSDPPFEVRG ANQWIKFKSV S

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 30-390 of human PDHA1 (NP_000275.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:20 - 1:50

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PDHA1

Antigène: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Autre désignation: PDHA1 (PDHA1 Produits)

Synonymes: anticorps PDHA, anticorps PDHCE1A, anticorps PHE1A, anticorps Pdha-1, anticorps pdha, anticorps phe1a, anticorps pdhce1a, anticorps im:6895726, anticorps pdha1, anticorps wu:fd18b01, anticorps wu:fo96f03, anticorps zgc:73271, anticorps zgc:86692, anticorps Pdha1, anticorps wu:fp73b04, anticorps zgc:92705, anticorps NI36_05250, anticorps pdha1-a, anticorps pdha1-b, anticorps pyruvate dehydrogenase E1 alpha 1 subunit, anticorps pyruvate dehydrogenase E1 alpha 1, anticorps pyruvate dehydrogenase (lipoamide) alpha 1, anticorps pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene, anticorps 2-oxo acid dehydrogenase, anticorps pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha, anticorps pyruvate dehydrogenase alpha subunit protein, anticorps pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit, anticorps precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit, anticorps pyruvate dehydrogenase, anticorps pyruvate dehydrogenase E1 alpha 1 subunit a, anticorps pyruvate dehydrogenase E1 alpha 1 subunit b, anticorps pyruvate dehydrogenase E1 component subunit alpha, anticorps pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog, anticorps PDHA1, anticorps Pdha1, anticorps pdha1, anticorps LOC719277, anticorps VNG_RS07485, anticorps RR_RS04695, anticorps pdhA1, anticorps pdha1a, anticorps pdha1b, anticorps NI36_RS05240, anticorps pdha1.S

Sujet: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PDHA1,PDHA,PDHAD,PDHCE1A,PHE1A,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Carbohydrate metabolism,Warburg Effect,PDHA1

Poids moléculaire: 40 kDa/43 kDa/44 kDa/47 kDa

ID gène: 5160

UniProt: P08559

Pathways: L'effet Warburg