PDE8B anticorps (Internal Region)
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- Antigène Voir toutes PDE8B Anticorps
- PDE8B (phosphodiesterase 8B (PDE8B))
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Épitope
- Internal Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PDE8B est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects Phosphodiesterase 8B (PDE8B) at internal domain.
- Purification
- Immunoaffinity chromatography
- Immunogène
- PDE8B antibody was raised against synthetic peptide from internal domain of human PDE8B.
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- Discover our top product PDE8B Anticorps primaire
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- Indications d'application
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Immunohistochemistry on paraffin sections (5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0,3 mg/mL
- Buffer
- PBS containing 0.09 % sodium azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- Antigène
- PDE8B (phosphodiesterase 8B (PDE8B))
- Autre désignation
- PDE8B (PDE8B Produits)
- Synonymes
- anticorps PDE8B, anticorps ADSD, anticorps PPNAD3, anticorps B230331L10Rik, anticorps C030047E14Rik, anticorps RNPDE8B, anticorps phosphodiesterase 8B, anticorps high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B, anticorps PDE8B, anticorps LOC100468338, anticorps pde8b, anticorps Pde8b
- Sujet
- Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX.Synonyms: 5'-cyclic phosphodiesterase 8B, ADSD, Cell proliferation-inducing gene 22 protein, High affinity cAMP-specific and IBMX-insensitive 3', PIG22, PPNAD3, Phosphodiesterase 8B, hsPDE8B
- ID gène
- 8622
- NCBI Accession
- NP_001025022
- UniProt
- O95263
- Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
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