ODC1 anticorps

N° du produit ABIN3026477

Détail du produit anti-ODC1 anticorps

Antigène: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ODC1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Attributs du produit: This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Purification: Protein G affinity chromatography

Immunogène: Recombinant human ODC-1 protein was used as the immunogen for this antibody.

Clone: ODC1-485

Isotype: IgG1 kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,WB: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the ODC-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur ODC1

Antigène: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Autre désignation: ODC-1 / Ornithine Decarboxylase 1 (ODC1 Produits)

Synonymes: anticorps CG8721, anticorps Dmel\\CG8721, anticorps dodc1, anticorps odc, anticorps fc54f04, anticorps fi06d08, anticorps CHUNP6922, anticorps wu:fc54f04, anticorps wu:fi06d08, anticorps odc2, anticorps xODC1, anticorps xodc2, anticorps DDBDRAFT_0204020, anticorps DDBDRAFT_0237755, anticorps DDB_0204020, anticorps DDB_0237755, anticorps ODC, anticorps odc1, anticorps ODC1, anticorps Odc, anticorps odc1-a, anticorps Ornithine decarboxylase 1, anticorps ornithine decarboxylase 1, anticorps ornithine decarboxylase, anticorps diaminopimelate decarboxylase, anticorps Orn/DAP/Arg decarboxylase 2 domain-containing protein, anticorps Diaminopimelate decarboxylase, anticorps Ornithine decarboxylase, anticorps ornithine decarboxylase 1 L homeolog, anticorps ornithine decarboxylase, structural 1, anticorps Odc1, anticorps odc1, anticorps ODC1, anticorps odc, anticorps RR_RS04895, anticorps ASA_RS06380, anticorps LOC100232922, anticorps odc1.L, anticorps odc-1

Sujet: This antibody recognizes a 53  kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

ID gène: 4953