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TSACC/C1orf182 anticorps (Middle Region)

TSACC Reactivité: Humain, Souris, Rat WB, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3029276
  • Antigène Tous les produits TSACC/C1orf182 (TSACC)
    TSACC/C1orf182 (TSACC) (TSSK6 Activating Co-Chaperone (TSACC))
    Épitope
    • 15
    • 5
    Middle Region
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 20
    Lapin
    Clonalité
    • 20
    Polyclonal
    Conjugué
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TSACC/C1orf182 est non-conjugé
    Application
    • 15
    • 13
    • 13
    • 7
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Purification
    Antigen affinity
    Immunogène
    An amino acid sequence from the middle region of human SIAH Interacting Protein (NTRWDYLTQVEKECKE) was used as the immunogen for this SIP antibody (100% homologous in human, mouse and rat).
    Isotype
    IgG
  • Indications d'application
    The stated application concentrations are suggested starting amounts. Titration of the SIP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the SIP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    TSACC/C1orf182 (TSACC) (TSSK6 Activating Co-Chaperone (TSACC))
    Autre désignation
    SIP (TSACC Produits)
    Synonymes
    anticorps SIP, anticorps TP53DINP1, anticorps TP53INP1A, anticorps TP53INP1B, anticorps Teap, anticorps p53DINP1, anticorps C1orf182, anticorps RP11-443G18.5, anticorps SSTK-IP, anticorps 1700021C14Rik, anticorps C3H1orf182, anticorps RGD1304953, anticorps tumor protein p53 inducible nuclear protein 1, anticorps TSSK6 activating cochaperone, anticorps TSSK6 activating co-chaperone, anticorps TP53INP1, anticorps TSACC, anticorps Tsacc
    Sujet
    CACYBP (Calcyclin-binding protein), also called SIP (SIAH Interacting Protein), is a protein that in humans is encoded by the CACYBP gene. The full-length SIP cDNA encodes a predicted 228-amino acid protein. Sequence analysis of the shortest cDNA derived by 2-hybrid screening revealed an 8-amino acid difference in the deduced open reading frame followed by a stop codon, resulting in a predicted 80-amino acid protein, SIP-short (SIPS). The CACYBP gene is mapped on 1q25.1. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. The C-terminal region of SIP that is homologous to SGT1 was able to complement defects in yeast strains containing SGT1 mutant alleles, demonstrating conservation of SGT1 and SIP protein function.
    UniProt
    Q9HB71
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