TSC1 anticorps (C-Term)
-
- Antigène Voir toutes TSC1 Anticorps
- TSC1 (Tuberous Sclerosis 1 (TSC1))
-
Épitope
- C-Term
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp TSC1 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogène
- An amino acid sequence from the C-terminus of human Tuberous Sclerosis 1 (QLHIMDYNETHHEHS) was used as the immunogen for this TSC1 antibody (100% rat homology).
- Isotype
- IgG
- Top Product
- Discover our top product TSC1 Anticorps primaire
-
-
- Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the TSC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
-
- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the TSC1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- Antigène
- TSC1 (Tuberous Sclerosis 1 (TSC1))
- Autre désignation
- TSC1 (Hamartin) (TSC1 Produits)
- Synonymes
- anticorps LAM, anticorps TSC, anticorps hamartin, anticorps mKIAA0243, anticorps tsc1, anticorps wu:fc38b04, anticorps fa99f04, anticorps wu:fa99f04, anticorps zgc:63657, anticorps TSC complex subunit 1, anticorps tuberous sclerosis 1, anticorps TSC complex subunit 1b, anticorps TSC complex subunit 1a, anticorps TSC1, anticorps Tsc1, anticorps tsc1b, anticorps tsc1, anticorps tsc1a
- Sujet
- TSC1 (Tuberous Sclerosis 1), also called Hamartin, is a human protein and gene. As part of a comprehensive strategy to identify the gene mutant in tuberous sclerosis-1, van Slegtenhorst et al.(1997) developed an overlapping contig of clones from the 1.4-Mb TSC1 region on chromosome 9. Benvenuto et al.(2000) showed that overexpression of the TSC1 gene in rat fibroblasts inhibits growth and causes changes in cell morphology. Van Slegtenhorst et al.(1998) showed that hamartin and tuberin associate physically in vivo, however, and that the interaction is mediated by predicted coiled-coil domains.
- UniProt
- Q92574
- Pathways
- Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation
-