Pkc beta 1
Reactivité: Rat, Humain, Souris
WB, FACS, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 555
Indications d'application
The stated application concentrations are suggested starting amounts. Titration of the PKC beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
-20 °C
Stockage commentaire
After reconstitution, the PKC beta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene. It is a member of the protein kinase C (PKC) gene family. Family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Family members also serve as major receptors for phorbol esters, a class of tumor promoters. PKC beta has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. It has been found that it is activated by oxidative conditions in the cell, induces phosphorylation of < a href=../search_result.php?search_txt=shc>p66 (SHC) and triggers mitochondrial accumulation of the protein after it is recognized by the prolyl isomerase < a href=../search_result.php?search_txt=pin1>PIN1.