Aurora Kinase C anticorps (C-Term)

N° du produit ABIN3030080

Détail du produit anti-Aurora Kinase C anticorps

Antigène: Aurora Kinase C (AURKC)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora Kinase C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified

Immunogène: A portion of the C-terminal region of the human protein was used as immunogen for this AURKC antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the AURKC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the AURKC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Aurora Kinase C

Antigène: Aurora Kinase C (AURKC)

Autre désignation: AURKC (AURKC Produits)

Synonymes: anticorps AURKC, anticorps AIE2, anticorps AIK3, anticorps ARK3, anticorps AurC, anticorps SPGF5, anticorps STK13, anticorps aurora-C, anticorps AIE1, anticorps ARK-3, anticorps IAK3, anticorps Stk13, anticorps aurora kinase C, anticorps AURKC, anticorps Aurkc

Sujet: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

UniProt: Q9UQB9

Pathways: Cycle Cellulaire, Maintenance of Protein Location