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BOC anticorps (AA 1002-1020)

BOC Reactivité: Rat, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3030172
  • Antigène Voir toutes BOC Anticorps
    BOC (Brother Of CDO (BOC))
    Épitope
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1002-1020
    Reactivité
    • 19
    • 16
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat, Souris
    Hôte
    • 31
    • 1
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BOC est non-conjugé
    Application
    • 13
    • 13
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogène
    Amino acids 1002-1020 (DDSTHQLLQPQDCCHLQKQ-mouse) were used as the immunogen for this BOC antibody (100% rat homology).
    Isotype
    IgG
    Top Product
    Discover our top product BOC Anticorps primaire
  • Indications d'application
    The stated application concentrations are suggested starting amounts. Titration of the BOC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the BOC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    BOC (Brother Of CDO (BOC))
    Autre désignation
    BOC (BOC Produits)
    Synonymes
    anticorps TTN, anticorps BOC, anticorps MGC146299, anticorps LOC100226489, anticorps 4732455C11, anticorps mFLJ00376, anticorps CDON2, anticorps BOC cell adhesion associated, oncogene regulated L homeolog, anticorps BOC cell adhesion associated, oncogene regulated, anticorps biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein, anticorps boc.L, anticorps BOC, anticorps boc, anticorps Boc
    Sujet
    Brother Of CDO, also known as 'Brother of CDON' and BOC are cell surface receptors of the immunoglobulin(Ig)/fibronectin type III repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail. The domain structure of BOC is similar to that of CDON, and the proteins share 38 to 80 % amino acid identity in the individual extracellular domains. The International Radiation Hybrid Mapping Consortium mapped the gene to chromosome 3. In contrast with CDON, the intracellular region of BOC was not essential for its ability to positively regulate differentiation. BOC is dependent on CDON for activity and that CDON/BOC complexes function to regulate myogenic differentiation. Wegorzewska et al.(2003) proposed that CDO and BOC play a role in the inverse relationship between differentiation and transformation of cells in the skeletal muscle lineage. The protein is expressed by commissural neurons, and targeted disruption of it in mouse resulted in the misguidance of commissural axons toward the floor plate.
    UniProt
    Q6AZB0
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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