2B4 anticorps (C-Term)
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- Antigène Voir toutes 2B4 (CD244) Anticorps
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp 2B4 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogène
- An amino acid sequence from the C-terminus of human Cluster of Differentiation 244 (RLSRKELENFDVYS) was used as the immunogen for this CD244 antibody.
- Isotype
- IgG
- Top Product
- Discover our top product CD244 Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the CD244 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the CD244 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
- Autre désignation
- CD244 (CD244 Produits)
- Synonymes
- anticorps CD244, anticorps 2B4, anticorps NAIL, anticorps NKR2B4, anticorps Nmrk, anticorps SLAMF4, anticorps C9.1, anticorps F730046O15Rik, anticorps Ly90, anticorps CD244 molecule, anticorps CD244 natural killer cell receptor 2B4, anticorps CD244, anticorps Cd244
- Sujet
- Cluster of Differentiation 244 is a human protein encoded by the CD244 gene. It is also known as Natural Killer Cell Receptor 2B4. Tangye et al.(1999) mapped the gene to 1q22. Suzuki et al.(2008) identified a functional single-nucleotide polymorphism(SNP) in the gene that contributes to rheumatoid arthritis susceptibility. Functional analysis by Boles et al.(1999) demonstrated that engagement of CD244 with specific antibody activates NK cytolytic activity. Using recombinant human NK cell-activating ligand CD244 fused to domains 3 and 4 of rodent Cd4 and flow cytometric analysis, Brown et al.(1998) demonstrated that CD48 binds to CD244. Watzl et al.(2000) showed that antibody-mediated cross-linking of the protein leads to its rapid tyrosine phosphorylation, which is necessary for CD244-mediated killer cell activity.
- UniProt
- Q9BZW8
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