COX1 anticorps (AA 318-599)

N° du produit ABIN3030661

Détail du produit anti-COX1 anticorps

Antigène: COX1 (Cytochrome C Oxidase Subunit I (COX1))

Épitope: AA 318-599

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 318-599) was used as the immunogen for this COX1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the COX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the COX1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur COX1

Antigène: COX1 (Cytochrome C Oxidase Subunit I (COX1))

Autre désignation: COX1 (COX1 Produits)

Synonymes: anticorps COX-1, anticorps COI, anticorps MTCO1, anticorps COX1, anticorps CoxI, anticorps prostaglandin-endoperoxide synthase 1, anticorps cytochrome c oxidase subunit I, anticorps cytochrome c oxidase subunit 1, anticorps cytochrome c oxidase 1, anticorps PTGS1, anticorps COX1, anticorps cox1

Sujet: Cyclooxygenase 1(COX1), also known as Prostaglandin-endoperoxide synthase (PTGS1) or Mitochondrial cytochrome c oxidase subunit 1, is the key enzyme in prostaglandin biosynthesis. The gene is approximately 40 kb long, with 11 protein-coding exons. It is 599 amino acid residues with a calculated molecular mass of approximately 68 kD. By analysis of a human/hamster somatic hybrid DNA panel, it was demonstrated that the gene maps to chromosome 9. COX1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

UniProt: P23219

Pathways: Proton Transport