CYP11B1 anticorps (C-Term)

N° du produit ABIN3030679

Détail du produit anti-CYP11B1 anticorps

Antigène: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP11B1 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human CYP11B1 (RNFYHVPFGFGMRQC) was used as the immunogen for this CYP11B1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the CYP11B1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CYP11B1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CYP11B1

Antigène: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Autre désignation: CYP11B1 (CYP11B1 Produits)

Synonymes: anticorps CPN1, anticorps CYP11B, anticorps FHI, anticorps P450C11, anticorps AA389061, anticorps Cyp11b, anticorps Cyp11b-1, anticorps Cp11ba, anticorps RATCP11BA, anticorps P450c11, anticorps cytochrome P450, family 11, subfamily B, polypeptide 1, anticorps cytochrome P450 family 11 subfamily B member 1, anticorps cytochrome P450, family 11, subfamily b, polypeptide 1, anticorps cytochrome P450, subfamily XI B, polypeptide 1, anticorps CYP11B1, anticorps Cyp11b1

Sujet: Cytochrome p450, family 11, subfamily B, polypeptide 1, also called Steroid 11-beta-hydroxylase or P450C11, is a steroid hydroxylase found in the zona fasciculata. The gene functions primarily in mitochondria in the zona fasciculata of the adrenal cortex to convert 11-deoxycortisol to cortisol and 11-deoxycorticosterone to corticosterone. CYP11B1 is a member of the cytochrome P450 superfamily of enzymes. mRNA is present in human cardiac tissue samples from left and right atria, aorta, apex, intraventricular septum, and atrioventricular node, as well as whole adult and fetal heart. Ventricles did not express CYP11B1. In patients with 11-beta-hydroxylase deficiency leading to hypertension and congenital adrenal hyperplasia, Pascoe et al. identified mutations in the CYP11B1 gene.

UniProt: P15538

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis