An amino acid sequence from the middle region of human Glutamate receptor 3 (RKAGYWNEYERFVPFSDQQ) was used as the immunogen for this GLUR3 antibody (100% homologous in human, mouse and rat).
GRIA3
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
RB34080
unconjugated
Indications d'application
The stated application concentrations are suggested starting amounts. Titration of the GLUR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
-20 °C
Stockage commentaire
After reconstitution, the GLUR3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. It is mapped to Xq25. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. In addition, GLUR3 has been shown to interact with GRIP1 and PICK1.