HSPH1 anticorps (AA 713-733)

N° du produit ABIN3031140

Détail du produit anti-HSPH1 anticorps

Antigène: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Épitope: AA 713-733

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Antigen affinity

Immunogène: Amino acids 713-733 (EVMEWMNNVMNAQAKKSLDQD-human) were used as the immunogen for this HSP105 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the HSP105 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Hsp105 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur HSPH1

Antigène: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Autre désignation: HSP105 (HSPH1 Produits)

Synonymes: anticorps hsp105, anticorps hsp105a, anticorps hsp105b, anticorps hsp110, anticorps hsph1b, anticorps Hsp105, anticorps HSP105, anticorps HSP105A, anticorps HSP105B, anticorps NY-CO-25, anticorps 105kDa, anticorps AI790491, anticorps Hsp110, anticorps hsp-E7I, anticorps hsph1, anticorps hsph1a, anticorps heat shock protein family H (Hsp110) member 1, anticorps heat shock protein family H (Hsp110) member 1 S homeolog, anticorps heat shock protein 105 kDa, anticorps heat shock 105kDa/110kDa protein 1, anticorps heat shock protein family H (Hsp110) member 1 L homeolog, anticorps hsph1, anticorps hsph1.S, anticorps HSPH1, anticorps LOC100546590, anticorps Hsph1, anticorps hsph1.L

Sujet: Heat shock protein 105, also called HSPH1 or HSP110, is a protein that in humans is encoded by the HSPH1 gene. Immunohistochemical analysis localizes HSP105 mainly in the cytoplasm. Database analysis indicates that both HSP105 isoforms are highly conserved during evolution. By analysis of radiation hybrids and human/rodent hybrid cell lines, the HSPH1 gene is mapped to chromosome 13. Both HSP105alpha and HSP105beta are upregulated in HeLa cells exposed to heat shock. HSP105alpha, but not HSP105beta, is also upregulate in response to other cell stresses. Following heat shock, HSP105 relocalizes from a cytoplasmic to perinuclear position. Additionally, it may constitute a major determinant for both prognosis and treatment response in colorectal cancer.

UniProt: Q92598