IKBKB
Reactivité: Humain
ELISA, WB, IHC, IF
Hôte: Lapin
Monoclonal
3E1
unconjugated
Recombinant Antibody
Indications d'application
The stated application concentrations are suggested starting amounts. Titration of the IKKb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
-20 °C
Stockage commentaire
After reconstitution, the IKKb antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Antigène
IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
I kappa B kinase beta, also known as IKKb or NFKBIKB, is a protein that in humans is encoded by the IKBKB gene.< a href=../search_result.php?search_txt=ikba>IkBabinds and inhibits NF-kB in the cytoplasm. Activated IKKb phosphorylates IkBa, which frees< a href=../search_result.php?search_txt=nfkb>NFkBto translocate to the nucleus. It is found that mutations in IKKb had a more pronounced effect upon NFKB activation than did comparable mutations in< a href=../search_result.php?search_txt=ikk%20alpha>IKKa.