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IBSP anticorps (N-Term)

IBSP Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3031383
  • Antigène Voir toutes IBSP Anticorps
    IBSP (Integrin-Binding Sialoprotein (IBSP))
    Épitope
    • 15
    • 12
    • 9
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 56
    • 8
    • 8
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 50
    • 4
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 52
    • 6
    Polyclonal
    Conjugué
    • 27
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IBSP est non-conjugé
    Application
    • 49
    • 22
    • 13
    • 13
    • 13
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogène
    An amino acid sequence from the N-terminus of human Bone Sialoprotein 2 (FSMKNLHRRVKIEDSEEN) was used as the immunogen for this IBSP antibody.
    Isotype
    IgG
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  • Indications d'application
    The stated application concentrations are suggested starting amounts. Titration of the IBSP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the IBSP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    IBSP (Integrin-Binding Sialoprotein (IBSP))
    Autre désignation
    IBSP / Bone Sialoprotein 2 (IBSP Produits)
    Synonymes
    anticorps BNSP, anticorps BSP, anticorps BSP-II, anticorps SP-II, anticorps Bsp, anticorps BSP II, anticorps BSPII, anticorps Bsp2, anticorps IBSP, anticorps integrin binding sialoprotein, anticorps integrin-binding sialoprotein, anticorps integrin-binding sialoprotein S homeolog, anticorps IBSP, anticorps Ibsp, anticorps ibsp.S, anticorps ibsp
    Sujet
    Integrin-binding sialoprotein, also known as Bone sialoprotein and BSP, is a major structural protein of the bone matrix. Bone sialoprotein is a predicted 35KD acidic glycoprotein that undergoes extensive posttranslational modifications and is visualized by western blot at up to 70KD. It constitutes approximately 12 % of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. The BSP gene is mapped to 4q22.1.
    UniProt
    P21815
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