KLF3 anticorps (N-Term)

N° du produit ABIN3031564

Détail du produit anti-KLF3 anticorps

Antigène: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF3 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the N-terminus of human KLF3 (SYPSNYMESMKPNKY) was used as the immunogen for this KLF3 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the KLF3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the KLF3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur KLF3

Antigène: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Autre désignation: KLF3 (KLF3 Produits)

Synonymes: anticorps BKLF, anticorps 9930027G08Rik, anticorps AL024007, anticorps Bklf, anticorps Tef-2, anticorps klf12, anticorps Kruppel like factor 3, anticorps Kruppel-like factor 3 (basic), anticorps KLF3, anticorps Klf3, anticorps klf3

Sujet: Kruppel-like factor 3 is a protein that in humans is encoded by the KLF3 gene. It is also known as BKLF (Basic kruppel-like factor). KLF3 is a member of the Krüppel-like factors family of transcription factors. It primarily represses transcription through the transcriptional corepressor C-terminal binding protein (CtBP). Suske et al.(2005) stated that the human gene maps to chromosome 4p14, and the mouse gene maps to chromosome 5C3.3. Suske et al.(2005) stated that the human and mouse KLF3 proteins contain 345 and 344 amino acids, respectively. Both have a characteristic zinc finger domain, but lack the N-terminal buttonhead box found in related SP transcription factors. The repression mediated through KLF3 is also partially dependent on the sumoylation of its K10 and K197. Within KLF3's C-terminal, which is highly conserved throughout the KLF family, resides three C2H2 zinc fingers that preferentially bind the site NRG GNG NGR.

UniProt: P57682