KLF8 anticorps (N-Term)
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- Antigène Voir toutes KLF8 Anticorps
- KLF8 (Kruppel-Like Factor 8 (KLF8))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KLF8 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogène
- An amino acid sequence from the N-terminus of human Kruppel-like factor 8 (MVDMDKLINNLEVQLNSE) was used as the immunogen for this KLF8 antibody.
- Isotype
- IgG
- Top Product
- Discover our top product KLF8 Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the KLF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the KLF8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- KLF8 (Kruppel-Like Factor 8 (KLF8))
- Autre désignation
- KLF8 (KLF8 Produits)
- Synonymes
- anticorps klf8, anticorps BKLF3, anticorps ZNF741, anticorps A830097P10Rik, anticorps ZNF74, anticorps Klf8-ps1, anticorps RGD1565831, anticorps Kruppel like factor 8, anticorps Kruppel-like factor 8, anticorps KLF8, anticorps klf8, anticorps Klf8
- Sujet
- Kruppel-like factor 8 is a protein that in humans is encoded by the KLF8 gene. It is also named as ZNF741, or BKLF3. Kruppel-like factor proteins all contain a characteristic C-terminal DNA-binding domain containing three Kruppel-like zinc fingers, and they all recognize CACCC and GC boxes present in promoters and enhancers. The International Radiation Hybrid Mapping Consortium mapped the gene to the X chromosome (WI-18614). Suske et al.(2005) stated that the human gene maps to chromosome Xp11.21, and the mouse gene to chromosome XF3. van Vliet et al.(2000) identified a cDNA encoding KLF8, also called ZNF741. Expression of KLF8 or only its zinc fingers showed that the fingers could bind to a CACCC box. Sequence analysis predicted that the 359-amino acid protein contains a nuclear localization signal upstream of the zinc fingers, a valine-rich hydrophobic stretch, and a pro-val-asp-leu-ser(PVDLS) motif. Yeast 2-hybrid and GST pull-down analysis demonstrated that CTBP2 interacts with KLF8 through the PVDLS motif.
- UniProt
- O95600
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