LRP5 anticorps (C-Term)

N° du produit ABIN3031640

Détail du produit anti-LRP5 anticorps

Antigène: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRP5 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human Low-density lipoprotein receptor-related protein 5 (IHAVEEVSLEEFSAH) was used as the immunogen for this LRP5 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the LRP5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the LRP5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur LRP5

Antigène: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Autre désignation: LRP5 (LRP5 Produits)

Synonymes: anticorps Xlrp5, anticorps bmnd1, anticorps evr1, anticorps evr4, anticorps hbm, anticorps lr3, anticorps lrp5-A, anticorps lrp7, anticorps oppg, anticorps ops, anticorps opta1, anticorps vbch2, anticorps LRP5, anticorps LRP6, anticorps BMND1, anticorps EVR1, anticorps EVR4, anticorps HBM, anticorps LR3, anticorps LRP7, anticorps OPPG, anticorps OPS, anticorps OPTA1, anticorps VBCH2, anticorps mKIAA4142, anticorps low-density lipoprotein receptor-related protein 5, anticorps LDL receptor related protein 5, anticorps LDL receptor related protein 5 L homeolog, anticorps low density lipoprotein receptor-related protein 5, anticorps LDL receptor related protein 5 like, anticorps LOC100147353, anticorps LRP5, anticorps lrp5.L, anticorps lrp5, anticorps Lrp5, anticorps LRP5L

Sujet: Low-density lipoprotein receptor-related protein 5 is a protein that in humans is encoded by the LRP5 gene. LRP5 is a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with diabetes mellitus type 1 in humans. This protein plays a key role in skeletal homeostasis. In addition to that, the binding of Axin to LRP5 is an important part of the Wnt signal transduction pathway, and it also acts as a target for the inhibitory effects of Dickkopf, another developmental protein, on Wnt signaling.

UniProt: O75197

Pathways: Signalisation WNT, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation