Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

MTDH anticorps (AA 101-270)

MTDH Reactivité: Humain, Souris, Rat WB, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3031760
  • Antigène Voir toutes MTDH Anticorps
    MTDH (Metadherin (MTDH))
    Épitope
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 101-270
    Reactivité
    • 49
    • 17
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 40
    • 7
    • 3
    Lapin
    Clonalité
    • 45
    • 5
    Polyclonal
    Conjugué
    • 28
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MTDH est non-conjugé
    Application
    • 40
    • 15
    • 13
    • 13
    • 11
    • 10
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Purification
    Antigen affinity
    Immunogène
    Human partial recombinant protein (AA 101-270) was used as the immunogen for this LYRIC antibody.
    Isotype
    IgG
    Top Product
    Discover our top product MTDH Anticorps primaire
  • Indications d'application
    The stated application concentrations are suggested starting amounts. Titration of the LYRIC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ICC: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Stock
    -20 °C
    Stockage commentaire
    After reconstitution, the LYRIC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène
    MTDH (Metadherin (MTDH))
    Autre désignation
    LYRIC (Metadherin) (MTDH Produits)
    Synonymes
    anticorps MGC75963, anticorps 2610103J23Rik, anticorps 3D3, anticorps 3D3/Lyric, anticorps AEG-1, anticorps AV353288, anticorps D8Bwg1112e, anticorps Lyric, anticorps AEG1, anticorps LYRIC, anticorps LYRIC/3D3, anticorps metadherin, anticorps mtdh, anticorps MTDH, anticorps Mtdh
    Sujet
    MTDH (Metadherin), also known as LYRIC or astrocyte elevated gene-1 protein (AEG-1), is a protein that in humans is encoded by the MTDH gene. It is involved in < a href=../search_result.php?search_txt=hif-1 alpha>HIF-1 alpha mediated angiogenesis, interacts with SND1 and is involved in RNA-induced silencing complex (RISC), and plays a very important role in RISC and miRNA functions. LYRIC induces an oncogene called Late SV40 factor (LSF/TFCP2) which is involved in thymidylate synthase (TS) induction and DNA biosynthesis synthesis. Late SV40 factor enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (< a href=../search_result.php?search_txt=mmp9>MMP9). LYRIC acts as an oncogene in melanoma, malignant glioma, breast cancer and hepatocellular carcinoma. It is highly expressed in these cancers and helps in progression and development of these cancers. It is induced by c-Myc oncogene and plays very important role in anchorage independent growth of cancer cells.
    ID gène
    92140
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
Vous êtes ici:
Support technique