MSH2 anticorps (AA 337-583)
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- Antigène Voir toutes MSH2 Anticorps
- MSH2 (Mismatch Repair Protein 2 (MSH2))
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Épitope
- AA 337-583
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MSH2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Purification
- Antigen affinity
- Immunogène
- Human partial recombinant protein (AA 337-583) was used as the immunogen for this MSH2 antibody.
- Isotype
- IgG
- Top Product
- Discover our top product MSH2 Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the MSH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the MSH2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- MSH2 (Mismatch Repair Protein 2 (MSH2))
- Autre désignation
- MSH2 (MSH2 Produits)
- Synonymes
- anticorps COCA1, anticorps FCC1, anticorps HNPCC, anticorps HNPCC1, anticorps LCFS2, anticorps AI788990, anticorps wu:fc06b02, anticorps wu:fc13e09, anticorps zgc:55333, anticorps ATMSH2, anticorps MUTS homolog 2, anticorps msh2, anticorps mutS homolog 2, anticorps mutS homolog 2 (E. coli), anticorps MUTS homolog 2, anticorps mutS homolog 2 L homeolog, anticorps MutS protein homolog 2, anticorps MSH2, anticorps Msh2, anticorps msh2, anticorps msh2.L
- Sujet
- MutS homolog 2 is a protein that in humans is encoded by the MSH2 gene, which is located on chromosome 2. It is a tumor suppressor gene and more specifically a caretaker gene that codes for a DNA mismatch repair (MMR) protein, MSH2 forms a heterodimer with MSH6 to make the human MutS< font face=symbol>a mismatch repair complex. It also dimerizes with MSH3 to form the MutS< font face=symbol>b DNA repair complex. MSH2 is involved in many different forms of DNA repair, including transcription-coupled repair, homologous recombination, and base excision repair. It has been found that it may also be a coactivator of ESR1-dependent gene expression.
- ID gène
- 4436
- Pathways
- Réparation de l'ADN, Production of Molecular Mediator of Immune Response
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