PGK1 anticorps (Middle Region)
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- Antigène Voir toutes PGK1 Anticorps
- PGK1 (Phosphoglycerate Kinase 1 (PGK1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PGK1 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogène
- An amino acid sequence from the middle region of human Phosphoglycerate Kinase 1 (FGTAHRAHSSMVGVN) was used as the immunogen for this PGK1 antibody (100% homologous in human, mouse and rat).
- Isotype
- IgG
- Top Product
- Discover our top product PGK1 Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the PGK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL, IHC-P: 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the PGK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- PGK1 (Phosphoglycerate Kinase 1 (PGK1))
- Autre désignation
- PGK1 (PGK1 Produits)
- Synonymes
- anticorps MIG10, anticorps PGKA, anticorps Pgk-1, anticorps Pgk, anticorps PGK, anticorps wu:fd59b07, anticorps wu:fj36g06, anticorps zgc:56252, anticorps zgc:77899, anticorps PGK1, anticorps phosphoglycerate kinase 1, anticorps pgk2, anticorps pgka, anticorps phosphoglycerate kinase 1, anticorps phosphoglycerate kinase 1 L homeolog, anticorps PGK1, anticorps Pgk1, anticorps pgk1, anticorps LOC100348124, anticorps pgk1.L
- Sujet
- Phosphoglycerate Kinase 1, also known as PGKA, is an enzyme that in humans is encoded by the PGK1 gene. Willard et al.(1985) used a cDNA for human PGK to map the functional PGK1 gene to Xq13. Disulfide bonds in secreted proteins are considered to be inert because of the oxidizing nature of the extracellular milieu. An exception to this rule is a reductase secreted by tumor cells that reduces disulfide bonds in the serine proteinase plasmin. Lay et al.(2000) showed that the plasmin reductase isolated from conditioned medium of fibrosarcoma cells is the glycolytic enzyme phosphoglycerate kinase. Recombinant phosphoglycerate kinase had the same specific activity as the fibrosarcoma-derived protein. Plasma of mice bearing fibrosarcoma tumors contained several-fold more phosphoglycerate kinase, as compared with mice without tumors.
- UniProt
- P00558
- Pathways
- Cellular Glucan Metabolic Process
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