Plakophilin 2 anticorps (C-Term)
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- Antigène Voir toutes Plakophilin 2 (PKP2) Anticorps
- Plakophilin 2 (PKP2)
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Plakophilin 2 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogène
- An amino acid sequence from the C-terminus of human PKP2 (KKTDFVNSRTAKAYHSLKD) was used as the immunogen for this Plakophilin 2 antibody (100% mouse homology).
- Isotype
- IgG
- Top Product
- Discover our top product PKP2 Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the Plakophilin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the Plakophilin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- Plakophilin 2 (PKP2)
- Autre désignation
- Plakophilin 2 (PKP2 Produits)
- Synonymes
- anticorps ARVD9, anticorps 1200008D14Rik, anticorps 1200012P04Rik, anticorps AA516617, anticorps Pkp2l, anticorps plakophilin 2, anticorps PKP2, anticorps Pkp2
- Sujet
- Plakophilin-2 is a protein that in humans is encoded by the PKP2 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. PKP2 is a constituent of the desmosomal plaque in simple epithelia, some stratified epithelia, and some nonepithelial cells. It is also enriched in the karyoplasm of cells of various types, including those lacking desmosomes. PKP proteins participate in linking cadherins to intermediate filaments in the cytoskeleton and this gene product may regulate the signaling activity of beta-catenin. Plakophilin-2 has been shown to interact with Desmoplakin, Plakoglobin and Desmoglein 1.
- UniProt
- Q99959
- Pathways
- Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
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