PF4 anticorps (AA 85-101)

N° du produit ABIN3032246

Détail du produit anti-PF4 anticorps

Antigène: PF4 (Platelet Factor 4 (PF4))

Épitope: AA 85-101

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PF4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Amino acids 85-101 (DLQAPLYKKIIKKLLES-human) were used as the immunogen for this CXCL4 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the CXCL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CXCL4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur PF4

Antigène: PF4 (Platelet Factor 4 (PF4))

Autre désignation: CXCL4 (PF4 Produits)

Synonymes: anticorps CXCL4, anticorps PF-4, anticorps SCYB4, anticorps Cxcl4, anticorps Scyb4, anticorps Pf4a, anticorps RATPF4A, anticorps PF4A, anticorps CXCL4L1, anticorps CXCL4V1, anticorps PF4-ALT, anticorps SCYB4V1, anticorps PF4, anticorps platelet factor 4, anticorps platelet factor 4 variant 1, anticorps PF4, anticorps Pf4, anticorps LOC703451, anticorps PF4V1, anticorps LOC100524373, anticorps LOC102181854, anticorps LOC100630489

Sujet: Chemokine (C-X-C motif) ligand 4, is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. It belongs to the CXC chemokine family. The gene contains 3 exons spanning approximately 1 kb. It is encoded on a 10-kb EcoRI fragment of genomic DNA. By in situ hybridization, the gene is mapped to chromosome 4q12-q21. CXCL4s major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, the cytokine probably has a role in inflammation and wound repair.

UniProt: P02776