Western Blot. Immunohistochemistry on Paraffin Sections (5 μg/mL). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
anticorps P53AIP1, anticorps tumor protein p53 regulated apoptosis inducing protein 1, anticorps TP53AIP1
Sujet
P53AIP1 is located in mitochondria and its overexpression results in growth suppression and apoptosis. The induction of p53AIP1 transcription in response to DNA damage is dependent on phosphorylation of p53 at Ser-46. The p53AIP1 gene has 3 major transcripts, designated alpha, beta and gamma.Synonyms: p53-regulated apoptosis-inducing protein 1, p53AIP1