RGS14 anticorps (C-Term)

N° du produit ABIN3032454

Détail du produit anti-RGS14 anticorps

Antigène: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS14 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human Regulator of G-protein signaling 14 (CTVLADQEVRLENR) was used as the immunogen for this RGS14 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the RGS14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the RGS14 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur RGS14

Antigène: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Autre désignation: RGS14 (RGS14 Produits)

Synonymes: anticorps RPIP1, anticorps MGC80558, anticorps RGS14, anticorps rgs14, anticorps wu:fi04g12, anticorps regulator of G protein signaling 14, anticorps regulator of G-protein signaling 14, anticorps regulator of G-protein signaling 14 L homeolog, anticorps regulator of G-protein signalling 14, anticorps regulator of G protein signaling 14a, anticorps RGS14, anticorps Rgs14, anticorps rgs14.L, anticorps rgs14, anticorps rgs14a

Sujet: Regulator of G-protein signaling 14 is a protein that in humans is encoded by the RGS14 gene. This gene encodes a member of the regulator of G-protein signaling family. By genomic sequence analysis, this gene is mapped to chromosome 5q35.3. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein(GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

UniProt: O43566

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling