STRA8 anticorps (AA 341-355)

N° du produit ABIN3032753

Détail du produit anti-STRA8 anticorps

Antigène: STRA8 (Stimulated By Retinoic Acid 8 (STRA8))

Épitope: AA 341-355

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STRA8 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Amino acids 341-355 (DDDVMLLKCLETFDD-rat) were used as the immunogen for this Stra8 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Stra8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Stra8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur STRA8

Antigène: STRA8 (Stimulated By Retinoic Acid 8 (STRA8))

Autre désignation: Stra8 (STRA8 Produits)

Synonymes: anticorps RGD1562852, anticorps stimulated by retinoic acid 8, anticorps stimulated by retinoic acid gene 8, anticorps STRA8, anticorps Stra8

Sujet: Stimulated by retinoic acid 8 is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons. And this gene is mapped to chromosome 7q31. Retinoic acid (RA) signaling was required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying expression in embryonic testis. Since RA signaling regulated Stra8 expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.

UniProt: D4ADQ4