BAG3 anticorps (AA 100-561)

N° du produit ABIN3042341

Détail du produit anti-BAG3 anticorps

Antigène: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Épitope: AA 100-561

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAG3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 3(BAG3) detection. Tested with WB, IHC-P in Human,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 3(BAG3) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: BCL2-associated athanogene 3
Protein Name: BAG family molecular chaperone regulator 3

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Bag3 recombinant protein (Position: H100-N561). Human Bag3 shares 84.1% amino acid (aa) sequence identity with mouse Bag3.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur BAG3

Antigène: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Autre désignation: BAG3 (BAG3 Produits)

Synonymes: anticorps bag3-A, anticorps MGC53113, anticorps zgc:100859, anticorps BAG3, anticorps ATBAG3, anticorps BCL-2-associated athanogene 3, anticorps T28J14.160, anticorps T28J14_160, anticorps BAG-3, anticorps BIS, anticorps CAIR-1, anticorps MFM6, anticorps AA407278, anticorps Bis, anticorps mg638, anticorps BCL2 associated athanogene 3 L homeolog, anticorps BCL2-associated athanogene 3, anticorps BCL2 associated athanogene 3, anticorps BCL-2-associated athanogene 3, anticorps Bcl2-associated athanogene 3, anticorps bag3.L, anticorps bag3, anticorps BAG3, anticorps Bag3

Sujet: BAG family molecular chaperone regulator 3(BAG3) is a member of a conserved family of cyto-protective proteins that bind to and regulate Hsp70 family molecular chaperones. BAG3 mutations are responsible for familial dilated cardiomyopathy. BAG3 polymorphisms are also associated with sporadic forms of the disease together with HSPB7 locus. In muscle cells, BAG3 cooperates with the molecular chaperones Hsc70 and HspB8 to induce the degradation of mechanically damaged cytoskeleton components in lysosomes. This process is called chaperone-assisted selective autophagy (CASA) and is essential for maintaining muscle activity in flies, mice and men.

Synonyms: BAG 3 antibody|BAG family molecular chaperone regulator 3 antibody|BAG-3 antibody|Bag3 antibody|BAG3_HUMAN antibody|Bcl 2 binding protein antibody|Bcl-2-associated athanogene 3 antibody|Bcl-2-binding protein Bis antibody|BCL2 associated athanogene 3 antibody|BCL2 binding athanogene 3 antibody|BIS antibody|Docking protein CAIR 1 antibody|Docking protein CAIR-1 antibody

ID gène: 9531

UniProt: O95817