HRG anticorps (AA 19-200)

N° du produit ABIN3042459

Détail du produit anti-HRG anticorps

Antigène: HRG (Histidine-Rich Glycoprotein (HRG))

Épitope: AA 19-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Histidine-rich glycoprotein(HRG) detection. Tested with WB, IHC-P in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Histidine-rich glycoprotein(HRG) detection. Tested with WB, IHC-P in Human.
Gene Name: histidine-rich glycoprotein
Protein Name: Histidine-rich glycoprotein

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HRG recombinant protein (Position: V19-V200). Human HRG shares 71% and 69% amino acid (aa) sequences identity with mouse and rat HRG, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for HRG is approximately 0.2 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur HRG

Antigène: HRG (Histidine-Rich Glycoprotein (HRG))

Autre désignation: HRG (HRG Produits)

Synonymes: anticorps AI265597, anticorps AW413091, anticorps D16jh2, anticorps D18020, anticorps Hprg, anticorps Hrgp, anticorps HPRG, anticorps HRGP, anticorps THPH11, anticorps HRG1, anticorps histidine rich glycoprotein, anticorps histidine-rich glycoprotein, anticorps HRG, anticorps LOAG_12427, anticorps LOC100597044, anticorps Hrg

Sujet: Histidine-rich glycoprotein (HRG) is a protein that in humans is encoded by the HRG gene. It is mapped to 3q27.3. HRG contains two cystatin-like domains and is located in plasma and platelets. The protein can bind heme, dyes and divalent metal ions. It also can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. HRG is thought to have multiple roles as a protein in the human blood, including roles in immunity, angiogenesis and coagulation.

Synonyms: DKFZp779H1622 antibody|Histidine proline rich glycoprotein antibody|Histidine rich glycoprotein antibody|HPRG antibody|HRGP antibody|Thrombophilia due to elevated HRG antibody

ID gène: 3273

UniProt: P04196