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POLH anticorps (AA 157-361)

POLH Reactivité: Humain, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3042492
  • Antigène Voir toutes POLH Anticorps
    POLH (Polymerase (DNA Directed), eta (POLH))
    Épitope
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 157-361
    Reactivité
    • 42
    • 12
    • 11
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 42
    • 3
    Lapin
    Clonalité
    • 44
    • 1
    Polyclonal
    Conjugué
    • 18
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POLH est non-conjugé
    Application
    • 32
    • 13
    • 13
    • 12
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Fonction
    Rabbit IgG polyclonal antibody for DNA polymerase eta(POLH) detection. Tested with WB in Human,Rat.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for DNA polymerase eta(POLH) detection. Tested with WB in Human,Rat.
    Gene Name: polymerase (DNA directed), eta
    Protein Name: DNA polymerase eta
    Purification
    Immunogen affinity purified.
    Immunogène
    E.coli-derived human POLH recombinant protein (Position: A157-R361). Human POLH shares 93.6% amino acid (aa) sequence identity with mouse POLH.
    Isotype
    IgG
    Top Product
    Discover our top product POLH Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Antigène
    POLH (Polymerase (DNA Directed), eta (POLH))
    Autre désignation
    POLH (POLH Produits)
    Synonymes
    anticorps POLH, anticorps fc50a12, anticorps wu:fc50a12, anticorps zgc:136881, anticorps zgc:152642, anticorps RAD30, anticorps RAD30A, anticorps XP-V, anticorps XPV, anticorps polymerase (DNA directed), eta S homeolog, anticorps DNA polymerase eta, anticorps polymerase (DNA directed), eta, anticorps putative DNA polymerase eta, anticorps polymerase (DNA directed), eta (RAD 30 related), anticorps polh.S, anticorps POLH, anticorps polh, anticorps Tb10.70.6190, anticorps LINJ_21_0690, anticorps Polh, anticorps LOC100443019
    Sujet
    DNA polymerase eta (Pol η), is a protein that in humans is encoded by the POLH gene. This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.

    Synonyms: DNA polymerase eta antibody|FLJ16395 antibody|FLJ21978 antibody|Polh antibody|POLH_HUMAN antibody|polymerase DNA directed eta antibody|RAD30 antibody|RAD30 homolog A antibody|RAD30A antibody|Xeroderma pigmentosum variant type protein antibody|XP V antibody|XPV antibody
    ID gène
    5429
    UniProt
    Q9Y253
    Pathways
    Réparation de l'ADN
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